B lymphocytes (B cells) develop immunocompetence in the bone marrow.Click to see full answer. Accordingly, where do B cells gain Immunocompetence?The thymus gland is the primary lymphoid organ for lymphocyte development. The red bone marrow produces B-lymphocytes (B cells) and T lymphocytes (T cells). B cells achieve immunocompetence (ability to recognize a specific antigen) in bone marrow. T cells migrate to the thymus gland, where they become immunocompetent.Furthermore, where does Immunocompetence develop? Site of antigen challenge and final differentiation to mature B and T cells Sites of development of immunocompetence as B or T cells; primary lymphoid organs Lymphocytes destined to become T cells migrate from bone marrow to the thymus and develop immunocompetence there. Also question is, where do B cells develop? B cells develop from hematopoietic stem cells (HSCs) that originate from bone marrow. HSCs first differentiate into multipotent progenitor (MPP) cells, then common lymphoid progenitor (CLP) cells.How do B cells become activated?B-cells are activated by the binding of antigen to receptors on its cell surface which causes the cell to divide and proliferate. Some stimulated B-cells become plasma cells, which secrete antibodies. Others become long-lived memory B-cells which can be stimulated at a later time to differentiate into plasma cells.
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